91在线视-亚洲综合无码一区二区三区-麻麻张开腿让我爽了一夜-成人午夜高潮a∨猛片-亚洲国产精品久久久久婷婷图片-国产亚洲精品久久精品69

產(chǎn)品中心您現(xiàn)在的位置：首頁 > 產(chǎn)品展示 > > 蛋白&肽 > Guanylyl cyclase α1β1 (soluble) (human), (recombin

Guanylyl cyclase α1β1 (soluble) (human), (recombin

更新時(shí)間：2022-01-28

簡要描述：

Guanylyl cyclase α1β1 (soluble) (human), (recombinant) (His-tag) (purified)
品牌： ENZO 產(chǎn)品貨號(hào)： ALX-201-177-C010 規(guī)格： 1*10µg
更多ENZO公司的產(chǎn)品，請(qǐng)咨詢一級(jí)代理商欣博盛生物

型號(hào)：廠商性質(zhì)：代理商瀏覽量：962

Guanylyl cyclase α1β1 (soluble) (human), (recombinant) (His-tag) (purified)

Product Details

Alternative Name:GTP pyrophosphate-lyase (cycling), sGCα1/sGCβ1

MW:~70kDa/~86kDa / subunit, respectively; heterodimer.

Source:Produced in Sf9 insect cells. Fused at the C-terminus to a His-tag. Produced in a baculovirus expression system.

EC:4.6.1.2

UniProt ID:Q02108 (GCα1), Q02153 (GCβ1)

Formulation:Liquid. In 50 mM Triethanolamine, pH 7.4, containing 150 mM NaCl, and 25% glycerol.

Purity:≥90% (SDS-PAGE)

Specific Activity:Basal: ≥0.050 µmol/mg/min.
- 100µM DEA NONOate (Prod. No. ALX-430-034) ≥10 µmol/mg/min.

Application Notes:Biophysical and enzymatic studies and drug screening.

Shipping:Shipped on Dry Ice

Long Term Storage:-80°C

Use/Stability:We do not recommend to store for longer periods after opening and thawing of the product.

Handling:Avoid freeze/thaw cycles.

Scientific Background:Guanylyl cyclase is part of the G protein signaling cascade that is activated by low intracellular calcium levels and inhibited by high intracellular calcium levels. In response to calcium levels, guanylyl cyclase synthesizes cGMP from GTP. cGMP keeps cGMP-gated channels open, allowing for the entry of calcium into the cell.

Regulatory Status:RUO - Research Use Only

Guanylyl cyclase α1β1 (soluble) (human), (recombinant) (His-tag) (purified) image
Figure: Spectral characteristics of basal and NO-treated purified human sGCα1β1 (3µM). Inset – Coomassie staining of 3µg of purified sGCα1β1. PM- protein marker.
Please mouse over
Guanylyl cyclase α1β1 (soluble) (human), (recombinant) (His-tag) (purified) image


Product Literature References

A new small molecule inhibitor of soluble guanylate cyclase: F. Mota, et al.; Bioorg. Med. Chem. 23, 5303 (2015), Abstract; Full Text
Surface plasmon resonance using the catalytic domain of soluble guanylate cyclase allows the detection of enzyme activators: F. Mota, et al.; Bioorg. Med. Chem. Lett. 24, 1075 (2014), Abstract; Full Text
Abacavir increases platelet reactivity via competitive inhibition of soluble guanylyl cyclase: P.D. Baum, et al.; AIDS 25, 2243 (2011), Application(s): Assay, Abstract; Full Text
Inhibition of nitric oxide-activated guanylyl cyclase by calmodulin antagonists: L.R. James, et al.; Br. J. Pharmacol. 158, 1454 (2009), Abstract; Full Text
Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase: H. Li, et al.; J. Biol. Chem. 283, 17855 (2008), Abstract; Full Text
Human soluble guanylate cyclase: functional expression, purification and structural characterization: D.N. Kosarikov, et al.; Arch. Biochem. Biophys. 388, 185 (2001), Abstract;
Human recombinant soluble guanylyl cyclase: expression, purification, and regulation: Y.C. Lee, et al.; PNAS 97, 10763 (2000), Abstract; Full Text
Purified soluble guanylyl cyclase expressed in a baculovirus/Sf9 system: stimulation by YC-1, nitric oxide, and carbon monoxide: M. Hoenicka, et al.; J. Mol. Med. 77, 14 (1999), Abstract;
Human soluble guanylate cyclase: functional expression and revised isoenzyme family: U. Zabel, et al.; Biochem. J. 335 (Pt 1), 51 (1998), Abstract; Full Text
Soluble guanylate cyclase purified from bovine lung contains heme and copper: R. Gerzer, et al.; FEBS Lett. 132, 71 (1981), Abstract;


如需購買或咨詢?cè)摦a(chǎn)品技術(shù)問題，請(qǐng)聯(lián)系ENZO一級(jí)代理商-欣博盛生物

留言框

  • 產(chǎn)品：

  • 您的單位：

  • 您的姓名：

  • 聯(lián)系電話：

  • 常用郵箱：

  • 省份：

  • 詳細(xì)地址：

  • 補(bǔ)充說明：

  • 驗(yàn)證碼：

    請(qǐng)輸入計(jì)算結(jié)果（填寫阿拉伯?dāng)?shù)字），如：三加四=7

主站蜘蛛池模板： 国产明星精品无码av换脸| 亚洲爆乳成av人在线视菜奈实| 欧洲吸奶大片在线看| 日本高清二区视频久二区| 人人妻人人澡人人爽人人dvd| 亚洲欧美日韩一区在线观看| 日本55丰满熟妇厨房伦| 性欧美俄罗斯极品| 国产拍揄自揄免费观看| 肥白大屁股bbwbbwhd| 亚洲乱亚洲乱妇| 国产精品爽爽v在线观看无码| 亚洲第一天堂国产丝袜熟女| 亚洲视频不卡| 裸身美女无遮挡永久免费视频 | 天天躁日日躁狠狠躁av| 精品av国产一二三四区| 国产九九在线视频| 99精品久久毛片a片| 在线永久看片免费的视频| 韩国日本三级在线观看| 久久亚洲色www成爱色| 日日碰狠狠躁久久躁综合网| 中文字字幕人妻中文| 精品人妻久久久久久888| 国农村精品国产自线拍| 人人妻碰人人免费| 国产午夜无码片在线观看网站| 五十路丰满中年熟女中出| 中文字幕av无码人妻| 国产亚洲精品成人aa片| 国产av亚洲精品久久久久| 日本熟妇人妻中出| 小罗莉极品一线天在线| 成人亚洲区无码区在线点播| 欧美亚洲日韩国产网站| 国产艹逼一区二区三区| 欧美日韩在线亚洲综合国产人| 亚洲春色在线视频| 久久精品九九亚洲精品天堂| 成人国产精品免费视频|